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Q.1
Mutations in which of the following genes lead to a rare form of muscular dystrophy?
a) lamin
b) tannin
c) gerotonin
d) rennin
Q.2
Most alterations in the genes occur during ____________________
a) cell division
b) motility
c) anaerobic conditions
d) sunlight exposure
Q.3
The chromosomal aberrations follow _____________________
a) chromosomal breakage
b) meiosis
c) mitosis
d) necrosis
Q.4
Which of the following is a rare genetic disorder?
a) Myeloma
b) Meningitis
c) Fanconi anemia
d) Breast cancer
Q.5
Which is not a type of chromosomal aberration?
a) mutations
b) inversion
c) translocation
d) duplication
Q.6
Inversions can lead to a deletion or duplication in the chromosome.
a) True
b) False
Q.7
The Philadelphia chromosome is the best studied example of ________________
a) inversion
b) translocation
c) deletion
d) duplication
Q.8
The translocated part of Philadelphia chromosome is found on chromosome ________
a) 4
b) 9
c) 11
d) 13
Q.9
Zygotes containing chromosomal deletion are produced by ___________
a) apoptosis
b) abnormal mitosis
c) abnormal meiosis
d) necrosis
Q.10
Unlike thepairs of chromosomes in human cells, chimpanzees havepairs of chromosomes.
a) True
b) False
Q.11
When was the first correlation between a chromosomal deletion and human disorder first developed?
a) 1963
b) 1973
c) 1983
d) 1993
Q.12
Partial trisomy is the presence of _____ copies of a gene.
a) 1
b) 2
c) 3
d) 4
Q.13
The cry-of-the-cat syndrome is due to a defect in chromosome __________
a) 2
b) 4
c) 5
d) 9
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