Q.1
Cyclin-CDK complex (here considering S cyclin) when active is responsible for phosphorylating several proteins and this often marks then for destruction by ubiquitination. What would be its effect on Cdt activity?
  • a) Activation
  • b) Inactivation
  • c) Destruction
  • d) Increased synthesis
Q.2
Which of these would you use as a competitive inhibitor for Cdt?
  • a) MCM 1
  • b) MCM 2
  • c) MCM 7
  • d) MCM 10
Q.3
What is the fate of phosphorylated Cdc 6?
  • a) It is transported outside nucleus
  • b) It is ubiquitinylated
  • c) It gets activated
  • d) It forms a complex with Cdt
Q.4
Pre-replication complex is necessary to initiate replication. It assembles in______________
  • a) Late Anaphase
  • b) G1 phase
  • c) S phase
  • d) Early Anaphase
Q.5
Which Cyclin-CDK complex will you find most active in M phase?
  • a) Cyclin A- CDK 2
  • b) Cyclin B- CDK 1
  • c) Cyclin D- CDK 2
  • d) Cyclin E- CDK 1
Q.6
What is the DNA composition of ARS?
  • a) A-T rich
  • b) G-C rich
  • c) Repeating A-T, G-C sequence
  • d) No specific sequence speciality
Q.7
In an experiment, you are working on mitochondrial chromosomes. Which polymerase will ensure accurate replication?
  • a) pol beta
  • b) pol delta
  • c) pol iota
  • d) pol gamma
Q.8
To your cultured cell lines, you add growth factors like cytokines which act through MAPK cascade pathway. Which transition will it trigger?
  • a) S->G2
  • b) M->Anaphase
  • c) G1->S
  • d) G2->M
0 h : 0 m : 1 s