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Drug Pharmaceutical Biotechnology
Drug Biotechnology Exam
Quiz 1
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Q.1
Any changes in fraction bioavailable, elimination half-life indicates nonlinearity of that particular drug.
a) True
b) False
Q.2
Which of the following creates nonlinearity in drug distribution and not in drug absorption?
a) When absorption is solubility or dissolution rate-limited
b) When absorption involves carrier-mediated transport systems
c) When a presystemic gut wall or hepatic metabolism attains saturation
d) Saturation of binding sites on plasma proteins
Q.3
Which one of these are correct Michaelis-Menten equation?
a) –dC/dt = Vmax C/Km+C
b) dC/dt = Vmax C/Km+C
c) –dC/dt = Vmax C/Km
d) –dC/dt = Km+C/Vmax C
Q.4
Which equation plot is being shown in the picture?
a) Michaelis-Menten plot
b) One compartment characteristics graph
c) Two compartment characteristics graph
d) Two compartment administered extravascularly characteristics plot
Q.5
In the given picture, which kinetic order the graph is following at the marked place?
a) 1st order kinetics
b) 2nd order kinetics
c) Mixed order kinetics
d) 1st order at higher doses
Q.6
In the given picture, which kinetic order the graph is following at the marked place?
a) 1st order kinetics
b) 2nd order kinetics
c) Mixed order kinetics
d) 1st order at higher doses
Q.7
In the given picture, which kinetic order the graph is following at the marked place?
a) 1st order kinetics
b) 2nd order kinetics
c) Mixed order kinetics
d) Zero-order rate
0 h : 0 m : 1 s
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