Q.1
Any changes in fraction bioavailable, elimination half-life indicates nonlinearity of that particular drug.
  • a) True
  • b) False
Q.2
Which of the following creates nonlinearity in drug distribution and not in drug absorption?
  • a) When absorption is solubility or dissolution rate-limited
  • b) When absorption involves carrier-mediated transport systems
  • c) When a presystemic gut wall or hepatic metabolism attains saturation
  • d) Saturation of binding sites on plasma proteins
Q.3
Which one of these are correct Michaelis-Menten equation?
  • a) –dC/dt = Vmax C/Km+C
  • b) dC/dt = Vmax C/Km+C
  • c) –dC/dt = Vmax C/Km
  • d) –dC/dt = Km+C/Vmax C
Q.4
Which equation plot is being shown in the picture?
Questiondrug-pharmaceutical-biotechnology-questions-answers4.jpg
  • a) Michaelis-Menten plot
  • b) One compartment characteristics graph
  • c) Two compartment characteristics graph
  • d) Two compartment administered extravascularly characteristics plot
Q.5
In the given picture, which kinetic order the graph is following at the marked place?
Questiondrug-pharmaceutical-biotechnology-questions-answers5.jpg
  • a) 1st order kinetics
  • b) 2nd order kinetics
  • c) Mixed order kinetics
  • d) 1st order at higher doses
Q.6
In the given picture, which kinetic order the graph is following at the marked place?
Questiondrug-pharmaceutical-biotechnology-questions-answers6.jpg
  • a) 1st order kinetics
  • b) 2nd order kinetics
  • c) Mixed order kinetics
  • d) 1st order at higher doses
Q.7
In the given picture, which kinetic order the graph is following at the marked place?
Questiondrug-pharmaceutical-biotechnology-questions-answers7.jpg
  • a) 1st order kinetics
  • b) 2nd order kinetics
  • c) Mixed order kinetics
  • d) Zero-order rate
0 h : 0 m : 1 s