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Drug Pharmaceutical Biotechnology
Pharmaceutical Biotechnology Assessment
Quiz 1
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Q.1
What term is given to “enzymes physically confined or localized in a certain defined region of space with retention of their catalytic activities, and which can be used repeatedly and continuous?
a) Localized enzymes
b) Localisation of enzymes
c) Immobilized enzymes
d) Catalysed enzymes
Q.2
Who reported the first industrial use of immobilized enzymes in 1967?
a) Robert Hook
b) Chibata and co-workers
c) James Watson
d) Kary Mullis
Q.3
The most common procedures of irreversible enzyme immobilization are covalent coupling, entrapment or micro-encapsulation and ____________
a) Hydrophilic linkage
b) Di-sulphide bonding
c) Covalent bonding
d) Cross-linking
Q.4
What is the method name that is based on the occlusion of an enzyme within a polymeric network that allows the substrate and products to pass through but retains the enzyme?
a) The entrapment method
b) Covalent coupling
c) Microencapsulation
d) Hollow fibre
Q.5
In physical adsorption the enzymes are attached to the matrix through hydrogen bonding, van der Waals forces, or hydrophobic interactions; whereas in ionic bonding, the enzymes are bound through?
a) Hydrophilic linkage
b) Di-sulphide bonding
c) Salt linkages
d) Cross-linking
Q.6
Which of the physical property of the matrices particularly determine the surface area and binding capacity?
a) Swelling behaviour
b) Mechanical strength
c) Compression behaviour
d) Pore parameters
Q.7
Which of the following are natural mineral polymers?
a) Cellulose
b) Dextran
c) Agar
d) Silica
Q.8
What is the name of the method used to attach enzymes to stationary solids by weak physical forces?
a) Absorption
b) Cross linking
c) Adsorption
d) Capillary action
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