Q.1
Absorption of drugs can be categorized into 2 classes, physicochemical properties of drugs and Dosage form of the drug, on the basis of drug dissolution.
  • a) True
  • b) False
Q.2
Which option will be the best example of the physicochemical properties of drugs?
  • a) Solubility, particle size, polymorphism, salt form, pseudopolymorphism, complexation, wettability, pH, Pressure of disintegration
  • b) Pressure of disintegration, polymorphism, salt form, pseudopolymorphism, complexation, wettability, pH
  • c) Solubility, particle size, polymorphism, salt form
  • d) Solubility, particle size, polymorphism, salt form, pseudopolymorphism, complexation, wettability
Q.3
For oral formulation, what should be the minimum aqueous solubility to avoid bioavailability problems?
  • a) 0.9%
  • b) 1%
  • c) 2%
  • d) 0.11%
Q.4
The total solid surface area of any particle is known as ___________
  • a) Absolute surface area
  • b) Effective surface area
  • c) Total surface area
  • d) Surface area
Q.5
Particle size and surface area of a drug are directly related to each other.
  • a) True
  • b) False
Q.6
Absolute surface area is proportional to the dissolution rate of a drug.
  • a) True
  • b) False
Q.7
In the case of hydrophobic drugs, micronization results in a decrease in effective surface area and thus fall is dissolution rate. Which of the below sentences cannot be a reason for the given statement?
  • a) The hydrophobic surface of the drugs adsorbs onto their surface which inhibits their wettability
  • b) The particles reaggregate to form larger particles due to their high surface free energy
  • c) Extreme reduction in the particle size imparts surface charges that may prevent wetting
  • d) Extreme reduction in the size brings the hydrophobic amino acids to the surface
Q.8
How the absolute surface area of hydrophobic drugs can be converted to their effective surface area?
  • a) Use of surfactant
  • b) Use of Hydrophobic diluents
  • c) Use of surfactant and hydrophilic diluents
  • d) No need of doing micronization
Q.9
Which one of these is not an example of hydrophilic diluents?
  • a) PVC
  • b) Dextrose
  • c) PVP
  • d) PEG
Q.10
The solvate can exist in different crystalline forms called as _________
  • a) Solvates
  • b) Pseudopolymorphs
  • c) Pseudopolymorphism
  • d) Hydrate
Q.11
Which form of a drug has greater solubility?
  • a) Anhydrous
  • b) Hydrate
  • c) Crystallised
  • d) Monohydrate
Q.12
Which one will be the easiest approach to enhance the solubility and dissolution of any drug?
  • a) Micronize the drug
  • b) Convert drug into their anhydrous form
  • c) Convert drug into their hydrous form
  • d) Convert drug into their salt form
Q.13
What is pH?
  • a) –ve log of H+ concentration
  • b) +ve log of H+ concentration
  • c) Log of H+ concentration
  • d) H+ concentration
Q.14
Which one of these is not an advantage of buffered aspirin tablets?
  • a) Enhanced bioavailability
  • b) Reduced gastric irritation
  • c) Increased stability
  • d) Increased ulcerogenic tendency
Q.15
Larger the size of the counterion, greater the solubility.
  • a) True
  • b) False
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