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Molecular Biology
Molecular Biology Basic
Quiz 1
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Q.1
For the correct addition of amino acid to the growing polypeptide chain which of the following does not play any role?
a) Loading of initiator tRNA to the P site
b) Loading of correct aminoacyl tRNA to the A site
c) Formation of peptide bond between the existing amino acid and the incoming amino acid
d) The formed tRNA with the growing polypeptide is translocated from the A site to the P site
Q.2
The events controlling the correct addition of amino acid is controlled by ____________ proteins.
a) 1
b) 2
c) 3
d) 4
Q.3
The auxillary protein required for the elongation of polypeptide is energy independent.
a) True
b) False
Q.4
Aminoacyl tRNA needs an escort to carry them to the ribosome bound mRNA.
a) True
b) False
Q.5
Once the tRNA is aminoacylated, EF-Tu binds to the tRNA at the ____________
a) 5’ end of the tRNA
b) 3’ end of the tRNA
c) Amino acid
d) Variable loop of tRNA
Q.6
The activation of GTPase activity of the enzyme EF-Tu occurs after its binding to the aminoacylated tRNA.
a) True
b) False
Q.7
The only fidelity testing of the translation is by observing the energy difference involved in the correct and incorrect base pairing.
a) True
b) False
Q.8
How many mechanisms are involved in the maintenance of the fidelity of translation?
a) 1
b) 2
c) 3
d) 4
Q.9
Which part of the large subunit helps in the formation of the peptide bond?
a) 5S rRNA
b) Proteins
c) 23S rRNA
d) 18S rRNA
Q.10
Which of the following steps is not required for the process of translocation?
a) Frame shift in hybrid states
b) Movement of P site tRNA to E site
c) Movement of A site tRNA to P site
d) Movement of ribosome by three nucleotides
Q.11
The completion of translocation requires the action of the factor _________________
a) EF-Tu
b) EF-G
c) eIF2
d) eIF4G
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