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Genetic Basis Of Inheritance Mcq
Quiz 11
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Q.1
Chromosomal condition of Down's syndrome is .... ...
0%
a) Allosomal hypoaneuploidy
0%
b) Autosomal aneuploidy
0%
c) Allosomal hyper-aneuploidy
0%
d) Partial autosomal deletion
Explanation
Answer : (b)
Q.2
Tay Sachs disease is due to ... .. [ AMU 2003 ]
0%
a) Sex-linked recessive gene
0%
b) Sex-linked dominant gene
0%
c) Autosomal dominant gene
0%
d) Autosomal recessive gene
Explanation
Answer : (d)
Q.3
Cri-du-char syndrome is due to chromosomal change involving ... ...[ AFMC 2008]
0%
a) Duplication
0%
b) inversion
0%
c) Deletion
0%
d) Translocation
Explanation
Answer : (c)
Q.4
Scientist who was awarded Nobel prize for finding genes to be linearly arranged on chromosomes was ... ... [ Kerala 2001 ]
0%
a) Wolf
0%
b) Punnet
0%
c) Morgan
0%
d) Knight
Explanation
Answer : (c)
Q.5
Which one is correctly matched? ... .. [ WB 2009 ]
0%
a) Sickle cell anaemia --- X-chromosome
0%
b) Haemophilia --- Y-chromosome
0%
c) Down's syndrome --- 21st chromosome
0%
d) Parkinson's disease --- XY chromosome
Explanation
Answer : (c)
Q.6
Mutation refers to sudden change in ... ... [ Pb PMT 1998 ]
0%
a) Phenotype
0%
b) Maturation time
0%
c) Metabolic rate
0%
d) Genetic make up
Explanation
Answer : (d)
Q.7
Haemophilic man marries a carrier woman. percentage of daughters becoming haemophilic shall be .... .. [ BHU 1990]
0%
a) 0%
0%
b) 50%
0%
c) 75%
0%
d) 100%
Explanation
A haemophilic man (XhY) marries a normal homozygous woman (XX). So, their daughter would have the genotype (XhX). As haemophilia is a recessive trait, the daughter would always be a carrier of the trait and can never be haemophilic. Answer : (a)
Q.8
gene for diabetes mellitus is ... ... [ BHU 2012 ]
0%
a) Autosomal dominant
0%
b) Autosomal recessive
0%
c) Sex-linked dominant
0%
d) Sex-linked recessive
Explanation
Answer : (a)
Q.9
Colchicine interferes with ... ... [kerala 2000]
0%
a) Chromosome replication
0%
b) Organization of spindle
0%
c) Chromosome condensation
0%
d) Incorporation of nitrogen bases
Explanation
Answer : (b)
Q.10
Human genome project was started in .... ....
0%
a) 1989
0%
b) 1990
0%
c) 1992
0%
d) 1995
Explanation
Answer : (b)
Q.11
out of A-T, G-C pairing bases of DNA may exists in alternate valency state called... .. [ WB2009]
0%
a) Tautomerisational mutation
0%
b) Analogue substitution
0%
c) point mutation
0%
d) Frame shift mutation
Explanation
Answer : (a)
Q.12
A mutation in DNA molecule involving replacement of one nucleotide base pair with another is .... ... [ MPPMT 2010]
0%
a) Point mutation
0%
b) Frame-shift mutation
0%
c) Deletion mutation
0%
d) A transposon
Explanation
Answer : (a)
Q.13
Cis-trans expression of gene is an example of .... [ DPMT 1996]
0%
a) Mutation
0%
b) Intragenic crossing over
0%
c) Intergenic crossing over
0%
d) Cytoplasmic inheritance
Explanation
Answer : (b)
Q.14
Heterochromatic region is .... .. [ Manipal 2004 ]
0%
a) Genetically more active
0%
b) Genetically less active
0%
c) loosely coiled region
0%
d) Lightly coloured region
Explanation
Answer : (b)
Q.15
Genes for colour blindness/sex linked traits are located on .. ... [ DPMT 2002 ]
0%
a) X-chromosome
0%
b) Y-chromosome
0%
c) X or Y-chromosome
0%
d) Both X and Y chromosomes
Explanation
Answer : (a)
Q.16
Depending upon distance between two genes, cross-over will vary from... ... [ AMU 2012 ]
0%
a) 50 -100%
0%
b) 75 -100%
0%
c) 10 ∼ 50%
0%
d) 0 - 50%
Explanation
Answer : (d)
Q.17
Select the correct bases of DNA, RNA and amino acid of beta chain causing sickle cell anaemia ... ... [ kerala 2009 ]
0%
a) DNA: CAC-GUG ; RNA: GAG ; Amino acid: Glutamic acid
0%
b) DNA: CAC-GTG ; RNA: GUG ; Amino acid: Valine
0%
c) DNA: CTC-GAG ; RNA: GUG ; Amino acid: Valine
0%
d) DNA: CAC-GTG ; RNA: GAG ; Amino acid: Glutamic acid
Explanation
Answer : (b)
Q.18
The symbol of empty circles used in pedigree analysis represnts ... .. [ manipal 2000]
0%
a) Normal females
0%
b) Normal males
0%
c) Affected females
0%
d) Affected males
Explanation
Answer : (a)
Q.19
Eukaryotic chromosome is made of ... .. [ RPMT 2006 ]
0%
a) DNA
0%
b) DNA + protein
0%
c) DNA + lipids
0%
d) RNA
Explanation
Answer : (b)
Q.20
phenotypically females having rudimentary ovaries, underdeveloped breasts, short stature, webbing neck, often subnormal intelligence suggests ... [ CET Chd. 2010]
0%
a) Down's syndrome
0%
b) Klinefelter's syndrome
0%
c) Turner's syndrome
0%
d) Haemophilic syndrome
Explanation
Answer : (c)
Q.21
Epicanthus is symptom of ... ... [ KCET 2001 ]
0%
a) Haploidy
0%
b) Turner's syndrome
0%
c) Down's syndrome
0%
d) Heteroploidy
Explanation
Answer : (c)
Q.22
Type of chromosomal aberration in diagram shows .... ..[ kerala 2005 ]
0%
a) Interstitial translocation
0%
b) Reciprocal translocation
0%
c) Paricentric translocation
0%
d) Interstitial translocation
Explanation
Answer : (c)
Q.23
Mental retardation in man associated with sex chromosomal abnormality is due to .... ... [ CBSE 1998 ]
0%
a) increase in X-complement
0%
b) decrease in X-complement
0%
c) large increase in Y-complement
0%
d) moderate increase in Y-complement
Explanation
Answer : (a)
Q.24
Patterns baldness, moustaches and beard in human males are examples of ... .. [ CBSE 2003 ]
0%
a) Sex-linked traits
0%
b) Sex differentiating traits
0%
c) Sex limited traits
0%
d) Sex determining traits
Explanation
Answer : (c)
Q.25
In human zygote male sex is determined by ... ... [ BHU 1995 ]
0%
a) Strength of father
0%
b) Nutrition of mother
0%
c) Composition of required chromosome pair
0%
d) None of the above
Explanation
Answer : (c)
Q.26
Addition of individual chromosomes is mutation called .... .. [ JKCMEE 2002 ]
0%
a) Polyploidy
0%
b) Structural mutation
0%
c) Polysomy
0%
d) Point mutation
Explanation
Answer : (c)
Q.27
The two eukaryotic organelles responsible for cytoplasmic inheritance are .... ... [ CBSE 2004]
0%
a) Lysosomes and mitochondria
0%
b) Chloroplasts and lysosomes
0%
c) Mitochondria and chloroplasts
0%
d) Mitochondria and Golgi complex
Explanation
Answer : (c)
Q.28
Genetic identity of human male is known by ... ... [ CBSE 1997 ]
0%
a) Nucleus
0%
b) Chloroplasts
0%
c) Cytoplasm
0%
d) Mitochondria
Explanation
Answer : (d)
Q.29
Which one can induce polyploidy? .... .. [ BHU 1992 ]
0%
a) Colchicine
0%
b) Acridines
0%
c) Ethylene
0%
d) Maleic hydrazide
Explanation
Answer : (a)
Q.30
Number of chromosomes in Geometrid Moth is .. ... [ Kerala 2000 ]
0%
a) 224
0%
b) 250
0%
c) 78
0%
d) 48
Explanation
Answer : (a)
Q.31
Colour blindness is due to one ... ... [ CPMT 1990 ]
0%
a) Recessive allele in females
0%
b) Dominant allele in females
0%
c) Dominant allele in males
0%
d) Recessive allele in males
Explanation
Answer : (d)
Q.32
A segment of chromosomes breaks and rejoins after 180° rotation. It is ... .. [ Kerala 2009 ]
0%
a) Duplication
0%
b) Reciprocal translocation
0%
c) Interstitial translocation
0%
d) Inversion
Explanation
Answer : (d)
Q.33
A few normal seedlings of tomato were kept in a dark room. After a few days they were found to have become white-coloured like albinos. Which of the following terms will you use to describe them? …[AIPMT 2014]
0%
a) Etiolated
0%
b) Defoliated
0%
c) Mutated
0%
d) Embolised
Explanation
Answer:(a)
Q.34
The movement of a gene from one linkage group to another is called: …[AIPMT 2015] Explanation is provided please click on
0%
a) Crossing over
0%
b) Inversion
0%
c) Duplication
0%
d) Translocation
Explanation
The movement of a gene from one linkage group to another is called translocation. It is a chromosome abnormality caused by rearrangement of parts between nonhomologous chromosomes. Answer:(a)
Q.35
Which is the most common mechanism of genetic variation in the population of a sexually-reproducing organism? …[AIPMT 2015]
0%
a) Recombination
0%
b) Transduction
0%
c) Chromosomal aberrations
0%
d) Genetic drift
Explanation
Answer:(a)
Q.36
Given below is a pedigree chart of a family with five children. It shows the inheritance of attached ear lobes as opposed to the free ones. The squares represent the male individuals and circles the female individuals, which one of the following conclusions drawn is correct ?
0%
a) The parents are homozygous recessive
0%
b) The trait is Y-linked
0%
c) The parents are homozygous dominant
0%
d) The parents are heterozygous
Explanation
Answer:(d)
Q.37
An abnormal human baby with 'XXX' sex chromosomes was born due to: …[AIPMT 2015]
0%
a) fusion of two sperms and one ovum
0%
b) formation of abnormal sperms in the father
0%
c) formation of abnormal ova in the mother
0%
d) fusion of two ova and one sperm
Explanation
Answer:(c)
Q.38
Which of the following most appropriately describes haemophilia ? …[AIPMT-2016]
0%
a) Recessive gene disorder
0%
b) X - linked recessive gene disorder
0%
c) Chromosomal disorder
0%
d) Dominant gene disorder
Explanation
Answer:(b)
Q.39
In higher vertebrates, the immune system can distinguish self-cells and non-self. If this property is lost due to genetic abnormality and it attacks self cells, then it leads to :- …[AIPMT-2016]
0%
a) Allergic response
0%
b) Graft rejection
0%
c) Auto-immune disease
0%
d) Active immunity
Explanation
Answer:(c)
Q.40
Pick out the correct statements : …[AIPMT-2016] (a) Haemophilia is a sex-linked recessive disease (b) Down's syndrome is due to aneuploidy (c) Phenylketonuria is an autosomal recessive gene disorder. (d) Sickle cell anaemia is a X-linked recessive gene disorder
0%
a) (a) and (d) are correct
0%
b) (b) and (d) are correct
0%
c) (a), (c) and (d) are correct
0%
d) (a), (b) and (c) are correct
Explanation
Answer:(d)
Q.41
Which of the following statements is not true for cancer cells in relation to mutations ? …[AIPMT-2016]B5
0%
a) Mutations in proto-oncogenes accelerate the cell cycle.
0%
b) Mutations destroy telomerase inhibitor.
0%
c) Mutations inactive the cell control.
0%
d) Mutations inhibit production of telomerase.
Explanation
Answer:(d)
Q.42
A cell at telophase stage is observed by a student in a plant brought from the field. He tells his teacher that this cell is not like other cells at telophase stage. There is no formation of cell plate and thus the cell is containing more number of chromosomes as compared to other dividing cells. This would result in :- …[AIPMT-2016]
0%
a) Aneuploidy
0%
b) Polyploidy
0%
c) Somaclonal variation
0%
d) Polyteny
Explanation
Answer:(b)
Q.43
Variation in gene frequencies within populations can occur by chance rather than by natural selection. This is referred to as …[NEET 2013]
0%
a) Genetic flow
0%
b) Genetic drift
0%
c) Random mating
0%
d) Genetic load
Explanation
Variation in gene frequencies within populations can occur by chance is called as genetic drift. Answer:(b)
Q.44
The incorrect statement with regard to Haemophilia is ….[NEET 2013]
0%
a) It is a sex-linked disease
0%
b) It is a recessive disease
0%
c) It is a dominant disease
0%
d) A single protein involved in the clotting of blood is affected
Explanation
Answer:(c)
Q.45
A disease caused by an autosomal primary non-disjunction is ….[NEET- 2017]
0%
a) Down's syndrome
0%
b) Klinefelter's syndrome
0%
c) Turner's syndrome
0%
d) Sickle cell anemia
Explanation
Down’s syndrome is caused by non-disjunction of 21st chromosome. Answer:(a)
Q.46
A colour blind man marries a woman with normal sight who has no history of colour blindness in her family. What is the probability of their grandson being colour blind ? [ ReAIPMT 2015]
0%
a) 0.25
0%
b) 0.5
0%
c) 1
0%
d) Nil
Explanation
Answer:(d)
Q.47
Select the correct statement ..[ NEET 2018]
0%
a) Franklin Stahl coined the term "linkage".
0%
b) Punnett square was developed by a British scientist.
0%
c) Spliceosomes take part in translation.
0%
d) Transduction was discovered by S. Altman.
Explanation
Answer : (b)
Q.48
A woman has an X-linked condition on one of her X chromosomes. This chromosome can be inherited by
0%
a) Only daughters
0%
b) Only sons
0%
c) Only grandchildren
0%
d) Both sons and daughters
Explanation
Answer : (d)
Q.49
Albinism is due to hereditary deficiency of enzyme .... ... [BHU 2003]
0%
a) Amylase
0%
b) Carbonic anhydrase
0%
c) Acetyl choline esterase
0%
d) Tyrosinase
Explanation
Answer : (d)
Q.50
ne centimorgan is equal to recombination frequency of .... ... [ DPMT 2005 ]
0%
a) 1
0%
b) 0.1
0%
c) 10
0%
d) 0.01
Explanation
Answer : (d)
0 h : 0 m : 1 s
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