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Genetic Basis Of Inheritance Mcq
Quiz 4
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Q.1
Which one is sex-related disease? [ JIPMER 2004 ]
0%
a) Christmas disease
0%
b) Klinefelter's syndrome
0%
c) Phenylketonuria
0%
d) Albinism
Explanation
Answer : (a)
Q.2
Which one is inherited disorder? Kerala 2003 ]
0%
a) Albinism
0%
b) AIDS
0%
c) Parkinson's disease
0%
d) leprosy
Explanation
Answer : (a)
Q.3
Which is the main category of mutation? [ CBSE 1999 ]
0%
a) Genetic mutation
0%
b) Zygotic mutation
0%
c) Somatic mutation
0%
d) All the above
Explanation
Answer : (a)
Q.4
Which one of the following is responsible for mental abnormalities in humans? [ MPPMT 1991]
0%
a) XXX and XY
0%
b) XX and XXX
0%
c) XO and XXXX
0%
d) XX and XO
Explanation
Answer : (c)
Q.5
Telomeres with repetitive DNA sequences ... .. [ CBSE 2007 ]
0%
a) Act as replicons
0%
b) Are transcription initiators
0%
c) Help in chromosome pairing
0%
d) Prevent chromosome loss
Explanation
Answer : (d)
Q.6
Assertion: Person suffering from haemophilia fail to produce blood clotting factor VIII Reason: Prothrombin producing platelets in such persons are found in very low concentration. .... [ AIIMS 2005 ]
0%
a) Both Assertion and Reason are true and Reason is the correct explanation of Assertion
0%
b) The Assertion and Reason are true but Reason is not correct explanation of Assertion
0%
c) Assertion is true but, Reason is false
0%
d) Assertion is false but, Reason is true
Explanation
Answer : (c)
Q.7
Which pteridophytes has the maximum chromosome number? .... ... [ JIPMER 1996 ]
0%
a) Ophioglossum reticulatum
0%
b) Azolla pinnata
0%
c) Lycopodium cernuum
0%
d) Selaginella apus
Explanation
Answer : (a)
Q.8
Deficiency of VIII factor leads to .... ... [ MPPMT 2007 ]
0%
a) Haemophilia A
0%
b) Haemophilia B
0%
c) Haemophilia C
0%
d) Haemophilia D
Explanation
Answer : (a)
Q.9
Cytoplasmic genes enter an individual through ... ... [ manipal 2000 ]
0%
a) Centrioles
0%
b) Ribosomes
0%
c) Golgi apparatus
0%
d) Mitochondria
Explanation
Answer : (d)
Q.10
Which one is sex-linked disorder? [ Manipur 2009 ]
0%
a) Sickle cell anaemia
0%
b) Albinism
0%
c) Haemophilia
0%
d) Phenylketonuria
Explanation
Answer : (c)
Q.11
The 'Christmas disease' patient lacks antihaemophilic .... ... [ KCET 2003 ]
0%
a) Homogentisic acid oxidase
0%
b) Factor VIII
0%
c) Factor XI
0%
d) Factor IX
Explanation
Answer : (d)
Q.12
Which is genetically transmitted trait? ... .. [ kerala 2004 ]
0%
a) Haemophilia
0%
b) Muscular dystrophy
0%
c) Colour blindness
0%
d) All the above
Explanation
Answer : (d)
Q.13
Gynandromorphy is .... ... [ CPMT 1996]
0%
a) Male with female traits
0%
b) Female with male traits
0%
c) Half male and half female
0%
d) None of the above
Explanation
Answer : (c)
Q.14
Theory proposed by Bridges is ... ... [ MPPMT 1999 ]
0%
a) Sex reversal
0%
b) Hormonal control of sex
0%
c) Genetic balance
0%
d) Development of Gynandromorphy
Explanation
Answer : (c)
Q.15
X-chromosome or X-body was first observed by .... ... [ HPPMT 2012 ]
0%
a) Mendel (1901)
0%
b) Castle ( 1910)
0%
c) Henking ( 1891)
0%
d) Bateson (1906)
Explanation
Answer : (c)
Q.16
An individual with cd genes was crossed with wild type ++. On test crossing F1, the progeny was +c 105, cd 880 and ++Distance between cd genes is ... ... [ AIIMS 1990]
0%
b) 5.5 map units
0%
a) 11 map units
0%
c) 44 map units
0%
d) 88 map units
Explanation
Answer : (a)
Q.17
A woman with normal vision but with colour blind father marries a colour blind man. The fourth child of the couple is a boy. this boy ... ... [ CBSE 2005 ]
0%
a) May or may not be colour blind
0%
b) Must be colour blind
0%
c) Must have normal vision
0%
d) Will be partially colour blind due to being heterozygous
Explanation
Answer : (a)
Q.18
An inborn error of metabolism which eventually affects mental development is .... .. [ HPPMT 2001 ]
0%
a) Albinism
0%
b) Phenylketonuria
0%
c) Anaemia
0%
d) Bleeder's disease
Explanation
Answer : (b)
Q.19
Gene is formed of ... ... [ BHU 2002]
0%
a) Polynucleotide
0%
b) Histone
0%
c) Hydrocarbons
0%
d) Lipoprotein
Explanation
Answer : (a)
Q.20
Which is functional unit of inheritance? [ Har PMT 2005 ]
0%
a) Cistron
0%
b) Intron
0%
c) Chromosome
0%
d) Gene
Explanation
Answer : (d)
Q.21
Given below is a highly simplified representation of the human sex chromosomes from a karyotype The genes a and b could be of .... [ AIIMS 2006 ]
0%
a) Colour blindness and body height
0%
b) Attached earlobe and Rhesus blood group
0%
c) Haemophilia and red green colour blindness
0%
d) Phenylketonuria and haemophilia
Explanation
Answer : (c)
Q.22
Free Martin is due to .... ... [ MPPMT 1997 ]
0%
a) Sex reversal by gene
0%
b) Environmental control of sex
0%
c) Hormonal control of sex
0%
d) Sex determination by chromosome
Explanation
Answer : (c)
Q.23
A normal woman whose father was colour blind marries a colour blind man. What percentage of girls born to these parents would by colour blind .... ... [ JIPMER 2002 ]
0%
a) 100%
0%
b) 75%
0%
c) 50%
0%
d) 25%
Explanation
Answer : (c)
Q.24
Bateson used the terms coupling and repulsion for linkage and crossing over. Name the correct parental or coupling type along with its cross over or repulsion.. .... [ CBSE 1990 ]
0%
a) Coupling AABB, aabb; Repulsion AABB AAbb
0%
b) Coupling AAbb, aaBB; Repulsion Aa Bb, aabb
0%
c) Coupling aaBB, aabb; Repulsion AABB, aabb
0%
d) Coupling AABB, aabb; Repulsion AAbb, aaBB
Explanation
Answer : (d)
Q.25
In Melandrium , sex determination is of ... ... [ Kerala 2003]
0%
a) XX - XO
0%
b) ZZ - ZW
0%
c) XX - XY
0%
d) XX - XO
Explanation
In Melandrium female individuals carry XX sex chromosomes and male individual carry XY sex chromosomes. Answer : (c)
Q.26
Non genetic sex determination occurs in ... ... [ WB 2007 ]
0%
a) Bonellia
0%
b) Cow
0%
c) Birds
0%
d) Fruit fly
Explanation
Answer : (a)
Q.27
Frequency of Down's syndrome increases when maternal age is ... .. [ Odisha 2004 ]
0%
a) Below 35 years
0%
b) Above 35 years
0%
c) At the time of first pregnancy
0%
d) After bearing three children
Explanation
Answer : (b)
Q.28
Genes are located in .... ... [ MPPMT 2012 ]
0%
a) Ribosomes
0%
b) Sphaerosomes
0%
c) Lysosomes
0%
d) Chromosomes
Explanation
Answer : (d)
Q.29
A colour blind daughter is born in case of .... .. [ BHU 1999 ]
0%
a) Colour blind mother, normal father
0%
b) Carrier mother, colour blind father
0%
c) Normal mother, colour blind father
0%
d) Carrier mother, normal blind father
Explanation
Answer : (b)
Q.30
Mr Kapoor has Bb autosomal gene pair and d allele sex-linked. What shall be proportion of Bb in sperms .... [ CBSE 1993]
0%
a) Zero
0%
b) 1/2
0%
c) 1/4
0%
d) 1/8
Explanation
Answer : (c)
Q.31
In Drosophila sex is determined by ... ..[CBSE 2003 ]
0%
a) X and Y chromosomes
0%
b) Ratio of pair of X-chromosomes to the pair of autosomes
0%
c) Ratio of number of X-chromosomes to the sets of autosomes
0%
d) Whether the egg is fertilized or develops parthenogenetically
Explanation
Answer : (c)
Q.32
Allosomes are the name of .... ... [ kerala 2001 ]
0%
a) Sex chromosomes
0%
b) Swellings on the chromosomes
0%
c) Chromosomes other than the ones which determine sex
0%
d) Nucleolusorganizing regions of chromosomes
Explanation
Answer : (a)
Q.33
As per Lyon's hypothesis, one of the two X-chromosomes undergoes hetero-chromatisation and is called ..... .. [ AMU 2002 ]
0%
a) Barr body
0%
b) Karyotypic body
0%
c) Genotypic body
0%
d) phenotypic body
Explanation
Answer : (a)
Q.34
Heterogamesis is .... ...
0%
a) Formation of two types of gametes
0%
b) Morphological distinction of male and female gametes
0%
c) Formation of two types of gametes by one sex and one type by other sex
0%
d) Formation of two types of gametes by both the sexes.
Explanation
Answer : (a)
Q.35
Cri-du-chat syndrome in humans is caused by ... ... [ CBSE 2006 ]
0%
a) Trisomy of 21st chromosome
0%
b) Loss of half of short arm of chromosome 5
0%
c) Loss of half of long arm of chromosome 5
0%
d) Fertilization of an XX egg by a normal Y-bearing sperm
Explanation
Answer : (b)
Q.36
Assertion: An organism with lethal mutation may not even develop beyond zygote stage Reason: All types of gene mutations are lethal ... ... [ AIIMS 2006 ]
0%
a) Both Assertion and Reason are true and Reason is the correct explanation of Assertion
0%
b) The Assertion and Reason are true but Reason is not correct explanation of Assertion
0%
c) Assertion is true but, Reason is false
0%
d) Assertion is false but, Reason is true
Explanation
Answer : (d)
Q.37
A single recessive allele which can express its effect should occur on ... ... [ AIIMS 1992 ]
0%
a) Any autosome
0%
b) Any chromosome
0%
c) X-chromosome of female
0%
d) X-chromosome of male
Explanation
Answer : (d)
Q.38
Assertion : Phenylketonuria is a recessive hereditary disease caused by failure of the body to oxides an amino acid phenylalanine to tyrosine because of defective enzyme Reason: It results in presence phenylalanine urine .... ... [ AIIMS 2007 ]
0%
a) Both Assertion and Reason are true and Reason is the correct explanation of Assertion
0%
b) The Assertion and Reason are true but Reason is not correct explanation of Assertion
0%
c) Assertion is true but, Reason is false
0%
d) Assertion is false but, Reason is true
Explanation
Answer : (a)
Q.39
Hypertrichosis ( hairy pinnae) is trait linked to ... .. [
0%
a) X - chromosome
0%
b) Y - chromosome
0%
c) Autosomes
0%
d) None of the above
Explanation
Answer : (b)
Q.40
Extra nuclear genes are found in .... ... [ AIIMS 2001 ]
0%
a) Plastids, not inherited
0%
b) Plasmid, not inherited
0%
c) Mitochondria, inherited from male
0%
d) Mitochondria, inherited from female
Explanation
Answer : (d)
Q.41
Klinefelter's syndrome has ... ... [ BHU 2006]
0%
a) 44 + XXY
0%
b) 44 + XO
0%
c) 45 + XY
0%
d) 66 + XXY
Explanation
Answer : (a)
Q.42
During preparation of gene map, recombination frequencies are additive over short distance but not exactly over long distance due to .... ... [ Har PMT 2001 ]
0%
a) Synaptonemal complex
0%
b) Inhibitor genes
0%
c) Multiple cross overs
0%
d) Mutations
Explanation
Answer : (c)
Q.43
Mutations are responsible for ... ... [ MPPMT 1996 ]
0%
a) Extinction of organisms
0%
b) Variations in population
0%
c) Increase in population
0%
d) Maintaining genetic continuity
Explanation
Answer : (b)
Q.44
A normal rate of spontaneous mutation is one in every .... ... [ odisha 2004 ]
0%
a) 103 - 105
0%
b) 105 - 107
0%
c) 106 - 109
0%
d) 107 - 1010
Explanation
Answer : (b)
Q.45
Frequency of an autosomal recessive lethal gene is 0.Frequency of carrier in a population of 200 individualsis ... .... [ AIIMS 1997 ]
0%
a) 72
0%
b) 96
0%
c) 104
0%
d) 36
Explanation
The frequency of the recessive allele is q = 0.4 (given) Hence, p = 1-0.4 = 0.6 (as p = 1- q) According to Hardy- Weinberg principle, p2 + 2pq + q2 = 1. hence, p2 = (0.6)2 => 0.36 q2 = (0.4)2 => 0.16 2pq = 0.48 since, 2pq is the frequency of hetrozygous carrier, = 0.48 X 200 = 96 Individuals Hardy- Weinberg principle allele frequencies in a population will not change from generation to generation. if the allele frequencies in a population with two alleles at a locus are p and q, then the expected genotype frequencies are p2, 2pq, and q2. This frequency distribution will not change from generation to generation once a population is in Hardy-Weinberg equilibrium. For example, if the frequency of allele A in the population is p and the frequency of allele a in the population is q, then the frequency of genotype AA = p2, the frequency of genotype Aa = 2pq, and the frequency of genotype aa = q2. If there are only two alleles at a locus, then p + q , by mathematical necessity, equals one. The Hardy-Weinberg genotype frequencies, p2 + 2pq + q2, represent the binomial expansion of (p + q)2, and also sum to one (as must the frequencies of all genotypes in any population, whether it is in Hardy-Weinberg equilibrium) Answer : (b)
Q.46
In the following human pedigree, the filled symbols represent the affected individuals. Identify the type of given pedigree. [ ReAIPMT 2015]
0%
a) X-linked dominant
0%
b) Autosomal dominant
0%
c) X-linked recessive
0%
d) Autosomal recessive
Explanation
Answer:(d)
Q.47
Ishihara chart are used by ophthalmologists for detecting .... .. [ BHU 2003 ]
0%
a) Eye infection
0%
b) Night blindness
0%
c) Colour blindness
0%
d) Finger prints
Explanation
Answer : (c)
Q.48
Down's syndrome is due to trisomy of 21st chromosome caused by ... ... [ CBSE 1998 ]
0%
a) Non disjunction during egg formation
0%
b) Non disjunction during sperm formation
0%
c) Addition of extra chromosome during mitosis of zygote
0%
d) Either A or B
Explanation
Answer : (d)
Q.49
A linkage group is defined as .... ....
0%
a) All the linked genes of a chromosomal pair
0%
b) Different groups of genes present on different chromosomes
0%
c) All the genes located on the same chromosome
0%
d) None of the above
Explanation
Answer : (a)
Q.50
Sex chromosomes of a female bird are ... ... [ Kerala 2008 ]
0%
a) XO
0%
b) ZZ
0%
c) ZW
0%
d) XX
Explanation
Answer : (c)
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