Q.1
Which one is sex-related disease? [ JIPMER 2004 ]
  • a) Christmas disease
  • b) Klinefelter's syndrome
  • c) Phenylketonuria
  • d) Albinism
Q.2
Which one is inherited disorder? Kerala 2003 ]
  • a) Albinism
  • b) AIDS
  • c) Parkinson's disease
  • d) leprosy
Q.3
Which is the main category of mutation? [ CBSE 1999 ]
  • a) Genetic mutation
  • b) Zygotic mutation
  • c) Somatic mutation
  • d) All the above
Q.4
Which one of the following is responsible for mental abnormalities in humans? [ MPPMT 1991]
  • a) XXX and XY
  • b) XX and XXX
  • c) XO and XXXX
  • d) XX and XO
Q.5
Telomeres with repetitive DNA sequences ... .. [ CBSE 2007 ]
  • a) Act as replicons
  • b) Are transcription initiators
  • c) Help in chromosome pairing
  • d) Prevent chromosome loss
Q.6
Assertion: Person suffering from haemophilia fail to produce blood clotting factor VIII Reason: Prothrombin producing platelets in such persons are found in very low concentration. .... [ AIIMS 2005 ]
  • a) Both Assertion and Reason are true and Reason is the correct explanation of Assertion
  • b) The Assertion and Reason are true but Reason is not correct explanation of Assertion
  • c) Assertion is true but, Reason is false
  • d) Assertion is false but, Reason is true
Q.7
Which pteridophytes has the maximum chromosome number? .... ... [ JIPMER 1996 ]
  • a) Ophioglossum reticulatum
  • b) Azolla pinnata
  • c) Lycopodium cernuum
  • d) Selaginella apus
Q.8
Deficiency of VIII factor leads to .... ... [ MPPMT 2007 ]
  • a) Haemophilia A
  • b) Haemophilia B
  • c) Haemophilia C
  • d) Haemophilia D
Q.9
Cytoplasmic genes enter an individual through ... ... [ manipal 2000 ]
  • a) Centrioles
  • b) Ribosomes
  • c) Golgi apparatus
  • d) Mitochondria
Q.10
Which one is sex-linked disorder? [ Manipur 2009 ]
  • a) Sickle cell anaemia
  • b) Albinism
  • c) Haemophilia
  • d) Phenylketonuria
Q.11
The 'Christmas disease' patient lacks antihaemophilic .... ... [ KCET 2003 ]
  • a) Homogentisic acid oxidase
  • b) Factor VIII
  • c) Factor XI
  • d) Factor IX
Q.12
Which is genetically transmitted trait? ... .. [ kerala 2004 ]
  • a) Haemophilia
  • b) Muscular dystrophy
  • c) Colour blindness
  • d) All the above
Q.13
Gynandromorphy is .... ... [ CPMT 1996]
  • a) Male with female traits
  • b) Female with male traits
  • c) Half male and half female
  • d) None of the above
Q.14
Theory proposed by Bridges is ... ... [ MPPMT 1999 ]
  • a) Sex reversal
  • b) Hormonal control of sex
  • c) Genetic balance
  • d) Development of Gynandromorphy
Q.15
X-chromosome or X-body was first observed by .... ... [ HPPMT 2012 ]
  • a) Mendel (1901)
  • b) Castle ( 1910)
  • c) Henking ( 1891)
  • d) Bateson (1906)
Q.16
An individual with cd genes was crossed with wild type ++. On test crossing F1, the progeny was +c 105, cd 880 and ++Distance between cd genes is ... ... [ AIIMS 1990]
  • b) 5.5 map units
  • a) 11 map units
  • c) 44 map units
  • d) 88 map units
Q.17
A woman with normal vision but with colour blind father marries a colour blind man. The fourth child of the couple is a boy. this boy ... ... [ CBSE 2005 ]
  • a) May or may not be colour blind
  • b) Must be colour blind
  • c) Must have normal vision
  • d) Will be partially colour blind due to being heterozygous
Q.18
An inborn error of metabolism which eventually affects mental development is .... .. [ HPPMT 2001 ]
  • a) Albinism
  • b) Phenylketonuria
  • c) Anaemia
  • d) Bleeder's disease
Q.19
Gene is formed of ... ... [ BHU 2002]
  • a) Polynucleotide
  • b) Histone
  • c) Hydrocarbons
  • d) Lipoprotein
Q.20
Which is functional unit of inheritance? [ Har PMT 2005 ]
  • a) Cistron
  • b) Intron
  • c) Chromosome
  • d) Gene
Q.21
Given below is a highly simplified representation of the human sex chromosomes from a karyotype The genes a and b could be of .... [ AIIMS 2006 ]
unit-7_ch-3_que_no-160_img_no1.png
  • a) Colour blindness and body height
  • b) Attached earlobe and Rhesus blood group
  • c) Haemophilia and red green colour blindness
  • d) Phenylketonuria and haemophilia
Q.22
Free Martin is due to .... ... [ MPPMT 1997 ]
  • a) Sex reversal by gene
  • b) Environmental control of sex
  • c) Hormonal control of sex
  • d) Sex determination by chromosome
Q.23
A normal woman whose father was colour blind marries a colour blind man. What percentage of girls born to these parents would by colour blind .... ... [ JIPMER 2002 ]
  • a) 100%
  • b) 75%
  • c) 50%
  • d) 25%
Q.24
Bateson used the terms coupling and repulsion for linkage and crossing over. Name the correct parental or coupling type along with its cross over or repulsion.. .... [ CBSE 1990 ]
  • a) Coupling AABB, aabb; Repulsion AABB AAbb
  • b) Coupling AAbb, aaBB; Repulsion Aa Bb, aabb
  • c) Coupling aaBB, aabb; Repulsion AABB, aabb
  • d) Coupling AABB, aabb; Repulsion AAbb, aaBB
Q.25
In Melandrium , sex determination is of ... ... [ Kerala 2003]
  • a) XX - XO
  • b) ZZ - ZW
  • c) XX - XY
  • d) XX - XO
Q.26
Non genetic sex determination occurs in ... ... [ WB 2007 ]
  • a) Bonellia
  • b) Cow
  • c) Birds
  • d) Fruit fly
Q.27
Frequency of Down's syndrome increases when maternal age is ... .. [ Odisha 2004 ]
  • a) Below 35 years
  • b) Above 35 years
  • c) At the time of first pregnancy
  • d) After bearing three children
Q.28
Genes are located in .... ... [ MPPMT 2012 ]
  • a) Ribosomes
  • b) Sphaerosomes
  • c) Lysosomes
  • d) Chromosomes
Q.29
A colour blind daughter is born in case of .... .. [ BHU 1999 ]
  • a) Colour blind mother, normal father
  • b) Carrier mother, colour blind father
  • c) Normal mother, colour blind father
  • d) Carrier mother, normal blind father
Q.30
Mr Kapoor has Bb autosomal gene pair and d allele sex-linked. What shall be proportion of Bb in sperms .... [ CBSE 1993]
  • a) Zero
  • b) 1/2
  • c) 1/4
  • d) 1/8
Q.31
In Drosophila sex is determined by ... ..[CBSE 2003 ]
  • a) X and Y chromosomes
  • b) Ratio of pair of X-chromosomes to the pair of autosomes
  • c) Ratio of number of X-chromosomes to the sets of autosomes
  • d) Whether the egg is fertilized or develops parthenogenetically
Q.32
Allosomes are the name of .... ... [ kerala 2001 ]
  • a) Sex chromosomes
  • b) Swellings on the chromosomes
  • c) Chromosomes other than the ones which determine sex
  • d) Nucleolusorganizing regions of chromosomes
Q.33
As per Lyon's hypothesis, one of the two X-chromosomes undergoes hetero-chromatisation and is called ..... .. [ AMU 2002 ]
  • a) Barr body
  • b) Karyotypic body
  • c) Genotypic body
  • d) phenotypic body
Q.34
Heterogamesis is .... ...
  • a) Formation of two types of gametes
  • b) Morphological distinction of male and female gametes
  • c) Formation of two types of gametes by one sex and one type by other sex
  • d) Formation of two types of gametes by both the sexes.
Q.35
Cri-du-chat syndrome in humans is caused by ... ... [ CBSE 2006 ]
  • a) Trisomy of 21st chromosome
  • b) Loss of half of short arm of chromosome 5
  • c) Loss of half of long arm of chromosome 5
  • d) Fertilization of an XX egg by a normal Y-bearing sperm
Q.36
Assertion: An organism with lethal mutation may not even develop beyond zygote stage Reason: All types of gene mutations are lethal ... ... [ AIIMS 2006 ]
  • a) Both Assertion and Reason are true and Reason is the correct explanation of Assertion
  • b) The Assertion and Reason are true but Reason is not correct explanation of Assertion
  • c) Assertion is true but, Reason is false
  • d) Assertion is false but, Reason is true
Q.37
A single recessive allele which can express its effect should occur on ... ... [ AIIMS 1992 ]
  • a) Any autosome
  • b) Any chromosome
  • c) X-chromosome of female
  • d) X-chromosome of male
Q.38
Assertion : Phenylketonuria is a recessive hereditary disease caused by failure of the body to oxides an amino acid phenylalanine to tyrosine because of defective enzyme Reason: It results in presence phenylalanine urine .... ... [ AIIMS 2007 ]
  • a) Both Assertion and Reason are true and Reason is the correct explanation of Assertion
  • b) The Assertion and Reason are true but Reason is not correct explanation of Assertion
  • c) Assertion is true but, Reason is false
  • d) Assertion is false but, Reason is true
Q.39
Hypertrichosis ( hairy pinnae) is trait linked to ... .. [
  • a) X - chromosome
  • b) Y - chromosome
  • c) Autosomes
  • d) None of the above
Q.40
Extra nuclear genes are found in .... ... [ AIIMS 2001 ]
  • a) Plastids, not inherited
  • b) Plasmid, not inherited
  • c) Mitochondria, inherited from male
  • d) Mitochondria, inherited from female
Q.41
Klinefelter's syndrome has ... ... [ BHU 2006]
  • a) 44 + XXY
  • b) 44 + XO
  • c) 45 + XY
  • d) 66 + XXY
Q.42
During preparation of gene map, recombination frequencies are additive over short distance but not exactly over long distance due to .... ... [ Har PMT 2001 ]
  • a) Synaptonemal complex
  • b) Inhibitor genes
  • c) Multiple cross overs
  • d) Mutations
Q.43
Mutations are responsible for ... ... [ MPPMT 1996 ]
  • a) Extinction of organisms
  • b) Variations in population
  • c) Increase in population
  • d) Maintaining genetic continuity
Q.44
A normal rate of spontaneous mutation is one in every .... ... [ odisha 2004 ]
  • a) 103 - 105
  • b) 105 - 107
  • c) 106 - 109
  • d) 107 - 1010
Q.45
Frequency of an autosomal recessive lethal gene is 0.Frequency of carrier in a population of 200 individualsis ... .... [ AIIMS 1997 ]
  • a) 72
  • b) 96
  • c) 104
  • d) 36
Q.46
In the following human pedigree, the filled symbols represent the affected individuals. Identify the type of given pedigree. [ ReAIPMT 2015]
unit-7_ch-3_que_no-190_img_no1.png
  • a) X-linked dominant
  • b) Autosomal dominant
  • c) X-linked recessive
  • d) Autosomal recessive
Q.47
Ishihara chart are used by ophthalmologists for detecting .... .. [ BHU 2003 ]
  • a) Eye infection
  • b) Night blindness
  • c) Colour blindness
  • d) Finger prints
Q.48
Down's syndrome is due to trisomy of 21st chromosome caused by ... ... [ CBSE 1998 ]
  • a) Non disjunction during egg formation
  • b) Non disjunction during sperm formation
  • c) Addition of extra chromosome during mitosis of zygote
  • d) Either A or B
Q.49
A linkage group is defined as .... ....
  • a) All the linked genes of a chromosomal pair
  • b) Different groups of genes present on different chromosomes
  • c) All the genes located on the same chromosome
  • d) None of the above
Q.50
Sex chromosomes of a female bird are ... ... [ Kerala 2008 ]
  • a) XO
  • b) ZZ
  • c) ZW
  • d) XX
0 h : 0 m : 1 s