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Quiz 19
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Q.1
ich of the following is correct regarding AIDS causative agent HIV?
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a) HIV is enveloped virus containing one molecule of single-stranded RNA and one molecule of reverse transcriptase
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b) HIV is enveloped virus that contains two identical molecules of single-stranded RNA and two molecules of reverse transcriptase
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c) HIV is enveloped retrovirus
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d) HIV does not escape but attacks the acquired immune response
Explanation
HIV is different in structure from other retroviruses. The HIV virion is ~100 nm in diameter. Its innermost region consists of a cone-shaped core that includes two copies of the (positive sense) ssRNA genome, the enzymes reverse transcriptase, integrase and protease, some minor proteins, and the major core protein. Answer:(b)
Q.2
ich cell of the body acts as HIV factories?
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a) HIV infected macrophages
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b) HIV infected Monocytes
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c) HIV infected cytotoxic T cells
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d) Helper T cells
Explanation
Answer:(a)
Q.3
ich of the following acts as filter of blood?
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a) Spleen
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b) Appendix
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c) Thymus
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d) Lymph nodes
Explanation
Answer:(a)
Q.4
tibody mediated immune system protect the body against:
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a) Viruses
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b) Bacteria
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c) Toxins
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d) All of these
Explanation
Answer:(d)
Q.5
tal paratopes in pentamer structure of IgM:
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a) 5
0%
b) 10
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c) 15
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d) 4
Explanation
Answer:(b)
Q.6
ich of the following drug is known for its effect on cardiovascular system?
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a) Ganja
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b) Heroin
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c) Datura
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d) Coke
Explanation
Answer:(a)
Q.7
e time lag between infection of HIV and appearance of symptoms usually is of:
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a) Few days to few months
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b) Few months to 3 -4years
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c) Few months to 5-10 years
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d) Few days to few years
Explanation
Answer:(c)
Q.8
inine, an important drug for treatment of malaria, is extracted from:
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a) Calyx of Cinnamon
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b) Bark of Cinchona
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c) Red ants
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d) Bark of Cinnamon
Explanation
Answer:(b)
Q.9
e spherical from of metacryptozoites is called _____
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a) Sporozoites
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b) Crypto schizont
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c) Trophozoite
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d) Gametocyte
Explanation
Answer:(c)
Q.10
ich of the following is not a type of antigen presenting cell in the body?
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a) Macrophages
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b) T cell
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c) B cell
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d) Dendritic cell
Explanation
Dendritic cells
Macrophages
B cells
Immune response
Innate immunity
Innate immunity
Adaptive immunity
Specific antigen receptors
No
No
Surface immunoglobulins
Location
Skin and mucosal epithelium (Langerhans cells), lymphoid tissue, connective tissue
Lymphoid tissue, connective tissue, body cavities
Blood, lymphoid tissue
Antigen type
Intracellular antigens and extracellular antigens
Extracellular antigens
Extracellular antigens
MHC molecule associated with antigen presentation
Class I MHC and class II MHC
Class II MHC
Class II MHC
Co-stimulation
High level B7 expression
Low level B7 expression, induced by bacteria/cytokines
No B7 expression unless induced upon activation by Th cells
The immune system contains three types of antigen-presenting cells, i.e., macrophages, dendritic cells, and B cells. Table shows properties and functions of these three types of antigen-presenting cells. Answer:(d)
Q.11
tch the column:
Wuchereria malayi
a. Aedes mosquito
Reservoir of erythrocytes
b. α interferons
Biological response modifier
c. Spleen
Chikungunya
d. Filariasis
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a) 1=d, 2=c, 3=b, 4=a
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b) 1=c, 2=a, 3=d, 4=b
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c) 1=d, 2=a, 3=b, 4=c
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d) 1=c, 2=d, 3=b, 4=a
Explanation
Answer:(a)
Q.12
ich of the following is used for the early detection with inherited susceptibility to certain cancers?
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a) Molecular technique
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b) Computed tomography
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c) Magnetic Resonance Imaging
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d) Radiography
Explanation
Answer:(b)
Q.13
ich one of the following sexually transmitted diseases (STDs) is not correctly matched with its pathogen?
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a) Cancroid – Haemophilus ducrei
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b) Chlamydia – Treponema pallidum
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c) Genital herpes – Type II herpes Simplex Virus (HSV – 2)
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d) Trichomoniasis – Trichomoniasis vaginalis
Explanation
Answer:(b)
Q.14
B test: AIDS - Immuno deficiency syndrome WIDAL test: ________ , ________
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a) Typhoid, increase in size of spleen & liver
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b) Typhoid, pain in stomach
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c) Typhoid, Burning in felt in intestine
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d) All of the given
Explanation
Answer:(d)
Q.15
ich one is responsible for doing disease shown in figure?
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a) Microsporum
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b) Trichophyton
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c) Epidermophyton
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d) All of the given
Explanation
Answer:(d)
Q.16
ich one of the following is not correctly matched?
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a) Anopheles culicifacies - Leishmaniasis
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b) Glossina palpalis - Sleeping sickness
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c) Culex pipiens - Filariasis
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d) Aedes aegypti - Yellow fever
Explanation
Answer:(a)
Q.17
atch the causative organism with their diseases:
Causative organism
Disease
a.
Haemophilus influenzae
Malignant malaria
b.
Entamoeba histolytica
Elephantiasis
c.
Plasmodium falciparum
Pneumonia
d.
Wuchereria brancofti
Typhoid
e.
Salmonella typhi
Amoebasis
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a) a=1, b=5, c=3, d=2, e=4
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b) a=5, b=1, c=3, d=4, e=2
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c) a=3, b=5, c=1, d=2, e=4
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d) a=1, b=3, c=5, d=2, e=4
Explanation
Answer:(c)
Q.18
entify the correct pairing: (i) Labelled antibodies – Detection of inherited susceptibility to cancer. (ii) Chemotherapy – Use of specific drugs to inhibit DNA replication in cancer cells. (iii) Radiotherapy – Lethal irradiation to detect the tumour cells. (iv) Proto-oncogene’s – Viral oncogenes that causes oncogenic transformation in normal cells. (v) Benign tumour – Do not remain confined to their original location.
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a) (i) and (ii)
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b) (iii) and (iv)
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c) (ii) and (v)
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d) (ii) only
Explanation
Answer:(d)
Q.19
ich one is correct for X, Y & Z? X - Trophozoite is formed in RBC. Y - Haemoglobin is broken down by haemozoin. Z - In RBC merozoites converted into gametocyte.
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a) X & Y are Right & Z is wrong
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b) X & Z are Right & Y is wrong
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c) Y & Z are Right & X is wrong
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d) X & Z are Wrong & Y is Right
Explanation
Answer:(b)
Q.20
mber of polypeptide chains present in a molecule of antibody is:
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a) 2
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b) 4
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c) 6
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d) 8
Explanation
Answer:(b)
Q.21
T – Hib vaccination is against:
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a) Diphtheria, Pertusis, Tetanus and Hepatitis B
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b) Diphtheria, Pertusis, Tetanus and Haemophilia B
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c) Diphtheria, Pertusis, Tetanus and Haemophilus influenzae B
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d) Diphtheria, Pertusis, Tetanus and Typhoid
Explanation
Answer:(c)
Q.22
IgM is Pentamerous and weight of antibody is around 1500000 Da. It is provided that weight of heavy chain of antibody is twice that of light chain. Then find the approximate weight of dimeric antibody IgA.
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a) More than 600kDa
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b) 550kDa
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c) 300kDa
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d) 30kDa
Explanation
Answer:(a)
Q.23
tch the columns:
Passive immunization
a. Hep B vaccine
Live bacterial vaccine
b. BCG
Live combination vaccine
c. ATS (Anti tetanus serum)
Recombinant antigenic vaccine
d. MMR
0%
a) 1=a, 2=b, 3=c, 4=d
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b) 1=c, 2=b, 3=d, 4=a
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c) 1=c, 2=d, 3=a, 4=b
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d) 1=b, 2=d, 3=c, 4=a
Explanation
Answer:(b)
Q.24
leen is not:
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a) Large reservoir of erythrocytes
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b) Bean shaped
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c) Mainly contains lymphocytes and phagocytes
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d) Lobed organ
Explanation
Answer:(d)
Q.25
....... can induce antibody formation only where they combine with larger protein molecules serving as carriers.
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a) Haptens
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b) Opsonins
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c) Epitope
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d) Antigenic determinants
Explanation
Answer:(a)
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