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NEET Biology MCQ
Quiz 1
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Q.1
Glycolysis is … … [ AIIMS 1996]
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a) C6H12O6 + 6O2 → 6CO2 + 6H2O
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b) C6H12O6 → 2 C2H5OH + 2CO2
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c) C6H12O6 → 2C3H4O3 + 4H+
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d) C3H4O3 + NADH → C2H5OH + CO2 + NAD+
Explanation
Answer : (c)
Q.2
oxygenation activity of RuBisCo enzyme in photorespiration leads to the formation of [NEET 2020]
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a) 1 molecule of 6-C compound
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b) 1 molecule of 4-C compound and 1 molecule of 2-C compound
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c) 2 molecules of 3-C compound
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d) 1 molecule of 3-C compound
Explanation
Answer : (d)
Q.3
Conversion of glucose to glucose-6-phosphate, the first irreversible reaction of glycolysis, is catalyzed by .... [NEET 2019]
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a) Aldolase
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b) Hexokinase
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c) Enolase
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d) Phosphofructokinase
Explanation
Hexokinase catalyse the conversion of Glucose to Glucose-6 phosphate. It is the first step of activation phase of glycolysis Answer : (b)
Q.4
What is the role of NAD+ in cellular respiration ? [NEET 2018]
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a) It is a nucleotide source for ATP synthesis.
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b) It functions as an electron carrier.
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c) It functions as an enzyme.
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d) It is the final electron acceptor for anaerobic respiration.
Explanation
Answer : (b)
Q.5
Which of these statements is incorrect ? [NEET 2018]
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a) Glycolysis operates as long as it is supplied with NAD that can pick up hydrogen atoms.
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b) Glycolysis occurs in cytosol.
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c) Enzymes of TCA cycle are present in mitochondrial matrix.
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d) Oxidative phosphorylation takes place in outer mitochondrial membrane.
Explanation
Answer : (d)
Q.6
The number of substrate level phosphorylations in one turn of citric acid cycle is .... [NEET 2020]
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a) Two
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b) Three
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c) Zero
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d) One
Explanation
Answer : (d)
Q.7
n mitochondria, protons accumulate in … .. [ CBSE mains 2011]
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c) inner membrane
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a) outer membrane
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b) Intermembrane space
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d) matrix
Explanation
The electrons from from NADH and FADH2 flow through the electron transport chain in the inner mitochondrial membrane generating a H+ buildup in the inner membrane space. Answer : (b)
Q.8
Oxidative phosphorylation refers to .. .. [ DPMT 2009]
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a) Anaerobic production of ATP
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b) Citric acid cycle production of ATP
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c) Production of ATP by chemiosmosis
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d) Alcoholic fermentation
Explanation
The production of ATP using the process of chemiosmosis in mitochondria is called oxidative phosphorylation. Oxidative phosphorylation is the process in which ATP is formed as a result of the transfer of electrons from NADH or FADH 2 to O2 by a series of electron carriers. where electron transport from the energy precursors from the citric acid cycle leads to the phosphorylation of ADP, producing ATP. Answer : (c)
Q.9
Match the columns … … [ kerla 2008]
a) 4C compound
1.Acetyl CoA
b) 2C Compound
2.Pyruvate
c) 5C Compound
Citric acid
d) 3C Compound
α-ketoglutaric acid
-- --
5.Malic acid
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a) a – 2, b – 5, c – 3, d – 1
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b) a – 5, b – 1, c – 4, d – 2
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c) a – 3, b – 1, c – 4, d – 2
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d) a – 5, b – 3, c -1, d – 2
Explanation
Malic acid is an organic compound with the molecular formula C4H6O5. It is a dicarboxylic acid that is made by all living organisms, contributes to the sour taste of fruits, and is used as a food additive.a – 5 Acetyl-CoA (acetyl coenzyme A) chemical formula C23H38N7O17P3S Its main function is to deliver the acetyl group to the citric acid cycle (Krebs cycle) to be oxidized for energy production b – 1 α-ketoglutaric acid Chemical formula: C5H6O5 c – 4 Pyruvate , the conjugate base, CH3COCOO-, is a key intermediate in several metabolic pathways throughout the cell. d – 2 Answer : (b)
Q.10
How many molecules of NADH are produced when four molecules of phosphoglyceraldehyde are converted into four molecules of pyruvate … .. [ Bih PMT 2006]
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a) 2
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b) 6
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c) 8
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d) 4
Explanation
given dtata belongs to Steps in Glycolysis In steps 4 and 5, aldolase and triose phosphate isomerase effectively convert one molecule of fructose 1,6-bisphosphate into two molecules of glyceraldehyde 3-phosphate. Thus, phase I of glycolysis requires energy in the form of two molecules of ATP and releases none of the energy stored in glucose. Phase two flow diagram is as follows Answer : (d)
Q.11
Cell respiration is carried out by … .. [ Odisha 2004]
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a) mitochondria
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b) Golgi bodies
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c) Ribosomes
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d) Chloroplasts
Explanation
Prokaryotic cells carry out cellular respiration within the cytoplasm or on the inner surfaces of the cells. More emphasis here will be placed on eukaryotic cells where the mitochondria are the site of most of the reactions. Answer : (a)
Q.12
Which one is the last electron acceptor over ETC in oxidative phosphorylation … ..[ AIIMS 2002]
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a) H2
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b) Cyt a3
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c) Cytb
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d) CO2
Explanation
Electron Transport Chain of Cellular Respiration - Oxidative Phosphorylation NADH is oxidized and FMN ( complex I) is reduced FMN is oxidized as it passes electrons to an iron sulfur protein, FeS(complex I) FeS is oxidized as it pass electrons to ubiquinone Q. FADH2 enters at complex II to , bypassing complex I Q passes electrons on to a succession of electron carriers ( in complex III and IIV), most of which are cytochromes Cyt a3, the last cytochrome passes electrons to oxygen Answer : (b)
Q.13
When malic acid is respiratory substrate, the amount of CO2 released is … ..[ EAMCET 2002]
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a) More than O2 consumed
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b) Less than O2 released
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c) Equal to O2 consumed
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d) CO2 is not released
Explanation
The respiratory quotient (or RQ or respiratory coefficient), is a dimensionless number used in calculations of basal metabolic rate (BMR) when estimated from carbon dioxide production. It is calculated from the ratio of carbon dioxide produced by the body to oxygen consumed by the body. C4H60 + 3 02 → 4C02 + 3H20 RQ = 4 C02/3 02 or 1.3 malic acid Since RQ > 1, CO2 > O2 Answer : (a)
Q.14
The number of ATP molecules produced by electron transport system from Krebs cycle intermediates in a single turn is … …[ AMU 1999]
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a) 11
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b) 12
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c) 14
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d) 16
Explanation
The net gain of high-energy compounds from one cycle is 3 NADH, 1 FADH2, and 1 GTP. NADH and FADH2 gives electrons to oxygen to produce water and ATP One NADH give 3ATP One FADH2 gives 2 ATP One GTP gives 1ATP Therefore total electrons produced = 3×3 + 2×1 +1 = 12ATP Answer : (b)
Q.15
Krebs cycle forms an important product .. .. [ AIIMS 1996]
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a) Acetyl CoA
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b) ADP
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c) ATP
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d) Water
Explanation
The Krebs cycle uses the two molecules of pyruvic acid formed in glycolysis and yields high-energy molecules of NADH and flavin adenine dinucleotide (FADH2), as well as some ATP Answer : (c)
Q.16
Choose the correct combination of labeling the number of carbon compounds in the substrate molecules involved in citric acid cycle … [ kerala 2006]
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a) a – 4C, b – 6C, c – 5C, d -4C, e – 4C
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b) a – 6C, b – 5C, c – 4C, d – 3C, e – 2C
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c) a – 2C, b – 3C, c – 4C, d- 5C, e – 6C
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d) a – 4C, b – 5C, c – 4C, d – 5C, e – 4C
Explanation
a) oxaloacetic acid: HO₂CCCH₂CO₂H. : 4 carbon atoms b) citric acid Formula: C6H8O7 : 6 carbon atoms c) α ketoglutaric acid Chemical formula : C5H6O5 : 5 carbon atom d) Succinic acid Formula: C4H6O4 : 4 carbon atoms e) Malic acid formula C4H6O5 : 4 carbon atoms Answer : (a)
Q.17
Mitochondrial electron transport chain is … ..[ JIPMER 2003]
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a) Cyclic phosphorylation
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b) Oxidative phosphorylation
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c) Matrix of mitochondria
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d) Oxysomes
Explanation
Oxidative phosphorylation is a process involving a flow of electrons through the electron transport chain, a series of proteins and electron carriers within the mitochondrial membrane. This flow of electrons allows the electron transport chain to pump protons to one side of the mitochondrial membrane Oxidative phosphorylation is the process in which ATP is formed as a result of the transfer of electrons from NADH or FADH2 to O2 by a series of electron carriers. This process, which takes place in mitochondria, is the major source of ATP in aerobic organisms Answer : (b)
Q.18
What is R.Q. of the reaction? .. ..[ Manipal 2005] 2C51H98O6 +145O2 → 102CO2 + 98 H2O
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a) 0.7
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b) 1.0
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c) 1.45
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d) 1.62
Explanation
RQ = moles of CO2 Produced/ moles ofO2 consumed RQ = 102/146 = 0.703 = 0.7 Answer : (a)
Q.19
Acetyl CoA forms a 6-C compound after combining with … .. [ BHU 2007]
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a) Malic acid
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b) Citric acid
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c) Succinic acid
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d) Oxaloacetic acid
Explanation
The first reaction of the Krebs cycle is the condensation of acetyl-CoA with oxaloacetate to form citrate, catalyzed by citrate synthase. Once oxaloacetate is joined with acetyl-CoA, a water molecule attacks the acetyl leading to the release of coenzyme A from the comple Answer : (d)
Q.20
A reaction catalysed by an enzyme not found in mitochondrial matrix … …[ EAMCET 2008]
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a) Conversion of pyruvic acid to acetyl CoA
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b) Oxidative decarboxylation of α-ketoglutaric acid
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c) Oxidation of succinic acid
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d) Cleavage of succinyl CoA
Explanation
Oxidation of Oxidation of succinic acid is not a part of Krebs cycle Answer : (c)
Q.21
Which is product of oxidative pentose phosphate pathway .. ..[ kerala 2007]
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a) Pyruvic acid
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b) Acetyl CoA
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c) NADH2
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d) NAD(P)H
Explanation
Answer : (d)
Q.22
Energy releasing process in which substrate is oxidized without an external electron acceptor is … … [ CBSE 2008]
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a) Aerobic respiration
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b) Fermentation
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c) Photorespiration
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d) Glycolysis
Explanation
Glycolysis is the first stage of the breakdown of glucose in the cytoplasm of the cell without using oxygen (electron acceptor). It is a stepwise process in which one molecule of glucose breaks into two molecules of pyruvic acid and a net gain of energy is 2 ATP and 2NADH2 molecules. The stepwise breakdown of the respiratory substrate to CO2 and H2O in presence of oxygen is referred as aerobic respiration. It is a catabolic process and generates a large amount of energy to form ATP. Anaerobic respiration in micro-organisms are called fermentation. These fermentation pathways consist of glycolysis with some extra reactions tacked on at the end. Alcoholic fermentation is a breakdown of glucose into ethyl alcohol and CO2 in presence of enzyme of micro-organism. Photorespiration is light-induced oxidation of photosynthetic intermediates with the help of oxygen without releasing energy. Answer : (d)
Q.23
Citric acid cycle is … … step in carbohydrate metabolism … .. [ CET Chd. 2010]
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a) First
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b) Second
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c) Third
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d) Fourth
Explanation
Glucose → Acetyl-CoA → Citric acid cycle (Krebs cycle) Answer : (c)
Q.24
Which processes of Krebs cycle are associated with both decarboxylation and dehydrogenation … ..[ Guj CET 2010]
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a) Succinate → Fumarate, Fumarate → Malate
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b) Malate → Oxaloacetate, Succinate → Fumarate
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c) α-Ketoglutaric acid → Succinate, Malate → Oxaloacetate
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d) Isocitrate → α-Ketoglutaric acid, α-Ketoglutaric acid → Succinate
Explanation
NAD+ covereted to NADH and removal of CO2 as shown in following equation Answer : (d)
Q.25
What is correct about the following statements …[ kerala 2012] a) Glycolysis occurs in cytoplasm of the cell b) Aerobic respiration occurs inside mitochondria c) ETS occurs in outer mitochondrial membrane d) C51H98O6 is tripalmitin e) RQ = volume of CO2 eliminated/volume of O2 consumed
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a) a, b and d are correct
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b) b,c and d are correct
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c) c,d and e are correct
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d) a,b,d and e are correct
Explanation
The electron transport chain for respiration occurs in the inner membrane layer of the mitochondria. In eukaryotes the ETC is located within mitochondria. Prokaryotes have ETC associated with inner plasma membrane Answer : (d)
Q.26
TCA cycle is named after … … [AFMC 2012]
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a) Embden
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b) Emerson
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c) Krebs
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d) Calvin
Explanation
The Krebs cycle (named after Hans Krebs) is a part of cellular respiration. Its other names are the citric acidity cycle, and the tricarboxylic acid cycle (TCA cycle). The "Krebs cycle" is a series of chemical reactions used by all aerobic organisms in their energy conversion processes Answer : (c)
Q.27
Enzyme helping in oxidative decarboxylation of pyruvic acid is … … [ AMU 1992]
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a) Pyruvic kinase
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b) Pyruvic dehydrogenase
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c) Malate dehydrogenase
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d) Succinic dehydrogenase
Explanation
Oxidative decarboxylation of pyruvic acid is catalyzed by the enzyme complex - pyruvate dehydrogenase. Pyruvate kinase is an enzyme that catalyzes the conversion of phosphoenolpyruvate and ADP to pyruvate and ATP in glycolysis Malate dehydrogenase (MDH) is an enzyme that reversibly catalyzes the oxidation of malate to oxaloacetate using the reduction of NAD+ to NADH. Succinic dehydrogenase enzymes catalyses the oxidation of succinate into fumarate in the Krebs cycle Answer : (b)
Q.28
Oxidation of a molecules of acetyl CoA produces … ..[ RPMT 1990]
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a) 12 ATP
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b) 15 ATP
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c) 6 ATP
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d) 19 ATP
Explanation
oxidation of acetyl CoA and the reduced coenzymes is coupled to the formation of a proton-motive force that powers ATP formation. Every acetyl-CoA yields 3 NADH + 1 FADH2 + 1 GTP (=ATP) We generally say that you get 3 ATPs per NADH and 2 per FADH2, 1ATP per GTP 3×3 = 9 ATP 2×1 = 2ATP 1×1 = 1ATP Total =12 ATP Answer : (a)
Q.29
R.Q. for glucose/ carbohydrate is … ..[ Bih. PMT 1990]
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a) 1
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b) 0.5
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c) 2
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d) 0.05
Explanation
For glucose, with the molecular formula, C6H12O6, the complete oxidation equation is C6H12O6 + 6 O2 → 6 CO2 + 6 H2O. Thus, the RQ= 6 CO2/ 6 O2=1 Answer : (a)
Q.30
End product of glycolysis is .. .. [ JIPMER 1990]
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a) Acetyl CoA
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b) Pyruvic Acid
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c) Glucose 1-phosphate
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d) Fructose 1-phosphate
Explanation
The net end products of glycolysis are two Pyruvate, two NADH, and two ATP Answer : (b )
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