In the budding yeast, activation of the GTP-binding protein Cdc42 occurs onbinding of an external signal (pheromone) to a G-protein-coupled receptor.Activation of Cdc42 promotes actin polymerization. Predict what would happen to actin polymerization, in comparison with pheromone-treated cells, in thefollowing cases.A. You add pheromone to an inhibitor of G-protein-coupled receptors.B. You add pheromone to a nonhydrolyzable analog of GTP.
  • decreasing the binding strength between subunits on filaments.
  • A. Less actin polymerization B. More actin polymerization
  • allows the behavior of microtubules called dynamic instability
  • Nuclear lamins will no longer disassemble properly during mitosis.
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