systems biology approach model the dynamic behavior of whole biological systems, gene circuits and protein interation networks, microarrays, cancer project iin different stages to look at the entire organism as one body
  • What is the goal of comparative genomic studies?
  • What are Hox genes?
  • Comparison Of Plant and Animal Development
  • How Systems are studied
ransposons may promote unequal crossing over during meiosis.
  • By what mechanism might transposons contribute to gene duplication?
  • How has gene duplication played a critical role in evolution?
  • What type of noncoding DNA comprises the largest portion of multicellular eukaryotic genomes?
  • How do retrotransposons differ from other transposons?
Hox genes encode transcription factors with a DNA-binding domain called a homeo box, and regulate development of the vertebrate body plan.
  • Number of Genes
  • Repetitive DNA
  • What are Hox genes?
  • Comparing Developmental Processes
usually SNPS with no ill effect, with duplications, inversions, deletios, studdy migrsation and diff betweem pop
  • Comparing Genomes Within a Species
  • Comparing Developmental Processes
  • Comparing Distantly related Species
  • Comparing Closely Related Speices
homeotic genes include homeobox (180-nuc eq), specifies (60-amino acid homeodomain, domain is a specific functioning part of protein)
  • Comparing Developmental Processes
  • Comparing Genomes Within a Species
  • Comparing Distantly related Species
  • Comparing Closely Related Speices
Most eukaryotes have larger genomes than most prokaryotes.
  • How has gene duplication played a critical role in evolution?
  • What was the main goal of the Human Genome Project (HGP)?
  • What is the goal of comparative genomic studies?
  • Which of the following statements about genome sizes is true?
the size of the genome in prokaryotesProkaryotic genomes are compact,
  • The number of genes correlates with _____
  • How do retrotransposons differ from other transposons?
  • Comparison Of Plant and Animal Development
  • What was the main goal of the Human Genome Project (HGP)?
-euks have low gene density-bacteria have mostly expressed genes-humans dom't mostly nc, complex reg seq
  • homeodomain
  • Gene Density
  • Genome SIZe
  • Number of Genes
Retrotransposons move via an RNA transcript, whereas other transposons do not.
  • How do retrotransposons differ from other transposons?
  • Which of the following statements about genome sizes is true?
  • How has gene duplication played a critical role in evolution?
  • What was the main goal of the Human Genome Project (HGP)?
comparing similar sequences and studying the characteristics of what differ, in humans and chimpanzees
  • Comparing Genomes Within a Species
  • Comparing Closely Related Speices
  • Comparing Distantly related Species
  • Comparing Developmental Processes
t produces redundant copies of existing genes, which are then free to mutate and adopt new functions.
  • Which of the following statements about genome sizes is true?
  • How do retrotransposons differ from other transposons?
  • How has gene duplication played a critical role in evolution?
  • What was the main goal of the Human Genome Project (HGP)?
to map all the human genes and determine the nucleotide sequence of the entire human genome
  • How has gene duplication played a critical role in evolution?
  • What is the goal of comparative genomic studies?
  • What was the main goal of the Human Genome Project (HGP)?
  • Which of the following statements about genome sizes is true?
clarifies evolutionary relationship among all diverged species
  • Comparing Distantly related Species
  • Comparing Genomes Within a Species
  • Comparing Closely Related Speices
  • Comparing Developmental Processes
-no need for morphogenesis on plants-relies on cascade of trans reg turning on off genesdevelopmental programs of plants and animals evolved seaprately mads-box in plants , hox in animals mostly
  • Comparing Closely Related Speices
  • Comparison Of Plant and Animal Development
  • Comparing Genomes Within a Species
  • Comparing Developmental Processes
-euk bigger than bact-euk have number of genes small compared to size of it , maybe due to alternative splicing
  • Genome SIZe
  • Gene Density
  • Comparing Genomes Within a Species
  • Number of Genes
to identify genes that are important for evolution of a particular species to identify homologues in model organisms for genes involved in human disease to study genetic variation within a species or a population to study how genomes evolve
  • What was the main goal of the Human Genome Project (HGP)?
  • What is the goal of comparative genomic studies?
  • Which of the following statements about genome sizes is true?
  • What are the steps in the shotgun approach to whole-genome sequencing?
60 amino acids length, binds to DNA when prtoein is a trans reg, can bind to and seg of DNA, but other domains in the protein control wha it binds to
  • Gene Density
  • homeodomain
  • Number of Genes
  • What are Hox genes?
-euk tend to have larger genome size-phenotype does not correlate to size
  • Genome SIZe
  • Number of Genes
  • The number of genes correlates with _____
  • Gene Density
15% of genome5% long dna 10,000 - 300k bp, simple sequence dNA of tandem repeats, 2to 5 nucs STR, also satellite DNA when centrifuged, centromeric and telomeric DNA
  • Repetitive DNA
  • Number of Genes
  • homeodomain
  • What are Hox genes?
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