Antisense nucleic acids interfere with protein synthesis.
  • True
  • False
Some bacterial cells are resistant to a variety of antimicrobials because they actively pumpthe drugs out of the cell.
  • True
  • False
Medications administered intravenously can provide much higher effective concentrationsthan other delivery methods.
  • True
  • False
Drugs known as beta-lactams interfere with bacterial (DNA/folic acid/cell wall) synthesis.
  • heavy metals
  • CELL WALL
  • isoniazid
  • tetracyclines
Secondary infections that result from the killing of some of the normal microbiota are called(antagonism/superinfections/resistance).
  • SUPERINFECTIONS
  • disinfectant.
  • ANTAGONISMS
  • tetracyclines
A microbe resistant to a variety of different antimicrobials is said to have(cross/drug/multiple) resistance.
  • MULTIPLE
  • CELL WALL
  • sulfonamide.
  • TOXICITY
Selective (action/toxicity/treatment) means that a given antimicrobial agent is more toxic to apathogen than to the host being treated.
  • INDEX
  • TOXICITY
  • tetrad
  • MULTIPLE
Organs that are commonly affected by drug toxicity include the kidneys and the liver.
  • True
  • False
A (bacteriocidial/bacteriostatic/minimum) concentration of a drug is one at which microbessurvive but are not able to grow and reproduce.
  • selective toxicity.
  • bacterial cells
  • synergism.
  • BACTERIOSTATIC
Some bacteria develop resistance to groups of drugs because the drugs are all structurallysimilar to each other; this is a phenomenon known as (cross/multiple/synergistic) resistance.
  • CROSS
  • False
  • INDEX
  • BACTERIOSTATIC
External infections can be treated by (intramuscular/surface/topical) administration, inwhich a drug is applied directly to the site of infection.
  • ANTAGONISMS
  • TOPICAL
  • isoniazid
  • TOXICITY
Beta-lactam antibiotics have an effect on which of the following types of cells? A. both animal and fungal cells B. bacterial cells D. animal cells E. fungal cells
  • antibiotic.
  • efflux pumps
  • bacterial cells
  • selective toxicity.
Competition between beneficial microbes and potential pathogens is called microbial(antagonisms/synergy/toxicity).
  • synergism.
  • antibiotic.
  • ANTAGONISMS
  • tetracyclines
The outer membrane of Gram-negative bacteria enables many antimicrobial drugs to enterthe cell more easily.
  • True
  • False
Paul Erhlich coined the term antibiotics for the "magic bullet" antimicrobials he pursued.
  • True
  • False
Any drug that acts against a disease is called a(n) (analog/antibiotic/chemotherapeutic)agent.
  • fluoroquinolones
  • sulfonamide.
  • inhibiting DNA replication.
  • CHEMOTHERAPEUTIC
Disruption of the normal microbiota can result in infections caused by which of thefollowing microbes?A) MycobacteriumB) Candida albicansC) Clostridium difficileD) both Mycobacterium and Clostridium difficileE) Candida albicans, Mycobacterium, and Clostridium difficile
  • Candida albicans, Mycobacterium, and Clostridium difficile
  • The antimicrobial is effective against a few microbes.
  • semisynthetic antimicrobial.
  • ANALOGS
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