Q.1
The chemically detoxified vaccines are very efficacious and inexpensive.
  • a) False
  • b) True
Q.2
Infection of HIV-1 is initiated by the binding of gpto CD4 and a co-receptor on host cells, triggering large scale conformational changes in gpthat eventually lead to membrane fusion.
  • a) False
  • b) True
Q.3
In chemically detoxified vaccines the structural epitopes of the pathogen should be destroyed.
  • a) True
  • b) False
Q.4
Neutralizing antibodies do not abrogate viral infectivity by which of the following mechanisms?
  • a) Inhibiting viral uncoating
  • b) Blocking virus attachment to host cells
  • c) Inducing the formation of non-infectious viral aggregates
  • d) Degrading the virus directly
Q.5
The chemical reaction in chemical detoxification should be reversible.
  • a) True
  • b) False
Q.6
Which of the following toxin does not have ADP-ribosylation activity?
  • a) Pertussis toxin
  • b) E. coli heat-labile toxin
  • c) Cholera toxin
  • d) Botulinum toxin A
Q.7
Influenza is a DNA virus that causes respiratory tract infections in mammals and some bird species.
  • a) True
  • b) False
Q.8
Which of the following is the pathogen of Pertussis?
  • a) Staphylococcus aureus
  • b) Salmonella typhi
  • c) Clostridium botulinum
  • d) Bordetella pertussis
Q.9
Antibiotic treatment is very effective in clearing Bordetella pertussis and the disease caused by it.
  • a) True
  • b) False
Q.10
Which of the following is not the way in which antibodies participate in host defense?
  • a) Opsonization
  • b) Enhance uptake by phagocytic cells
  • c) Activation of complement proteins
  • d) Directly destroy the antigen
Q.11
Dengue virus belongs to which of the following category?
  • a) Lentivirus
  • b) Coronavirus
  • c) Filovirus
  • d) Flavivirus
Q.12
Which of the following is the only way to control pertussis?
  • a) Antibiotic treatment
  • b) Heavy medications
  • c) Accurate diagnosis
  • d) Vaccination
Q.13
The first recombinant vaccine produced targeted the surface antigen of which of the following virus?
  • a) DENV1
  • b) Ebola virus
  • c) Hepatitis A virus
  • d) Hepatitis B virus
Q.14
Most viral vaccines are thought to work by which of the following technique?
  • a) Inducing the production of antigens
  • b) Inducing the production of cell wall
  • c) Inducing the production of cytosolic proteins
  • d) Inducing the production of antibodies
Q.15
Protein-based subunit vaccines initiate T cell-dependent activation of B cells.
  • a) False
  • b) True
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