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Protein Engineering
Protein Engineering Basic
Quiz 1
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Q.1
The chemically detoxified vaccines are very efficacious and inexpensive.
a) False
b) True
Q.2
Infection of HIV-1 is initiated by the binding of gpto CD4 and a co-receptor on host cells, triggering large scale conformational changes in gpthat eventually lead to membrane fusion.
a) False
b) True
Q.3
In chemically detoxified vaccines the structural epitopes of the pathogen should be destroyed.
a) True
b) False
Q.4
Neutralizing antibodies do not abrogate viral infectivity by which of the following mechanisms?
a) Inhibiting viral uncoating
b) Blocking virus attachment to host cells
c) Inducing the formation of non-infectious viral aggregates
d) Degrading the virus directly
Q.5
The chemical reaction in chemical detoxification should be reversible.
a) True
b) False
Q.6
Which of the following toxin does not have ADP-ribosylation activity?
a) Pertussis toxin
b) E. coli heat-labile toxin
c) Cholera toxin
d) Botulinum toxin A
Q.7
Influenza is a DNA virus that causes respiratory tract infections in mammals and some bird species.
a) True
b) False
Q.8
Which of the following is the pathogen of Pertussis?
a) Staphylococcus aureus
b) Salmonella typhi
c) Clostridium botulinum
d) Bordetella pertussis
Q.9
Antibiotic treatment is very effective in clearing Bordetella pertussis and the disease caused by it.
a) True
b) False
Q.10
Which of the following is not the way in which antibodies participate in host defense?
a) Opsonization
b) Enhance uptake by phagocytic cells
c) Activation of complement proteins
d) Directly destroy the antigen
Q.11
Dengue virus belongs to which of the following category?
a) Lentivirus
b) Coronavirus
c) Filovirus
d) Flavivirus
Q.12
Which of the following is the only way to control pertussis?
a) Antibiotic treatment
b) Heavy medications
c) Accurate diagnosis
d) Vaccination
Q.13
The first recombinant vaccine produced targeted the surface antigen of which of the following virus?
a) DENV1
b) Ebola virus
c) Hepatitis A virus
d) Hepatitis B virus
Q.14
Most viral vaccines are thought to work by which of the following technique?
a) Inducing the production of antigens
b) Inducing the production of cell wall
c) Inducing the production of cytosolic proteins
d) Inducing the production of antibodies
Q.15
Protein-based subunit vaccines initiate T cell-dependent activation of B cells.
a) False
b) True
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