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Q.1
BLAST often produces several short HSPs rather than a single aligned region.
True
False
Q.2
BLAST often produces several short HSPs rather than a single aligned region.
True
False
Q.3
BLAST might not find matches for very short sequences.
True
False
Q.4
Which of the following is not a benefit of BLAST?
Handling of gaps
Speed
More sensitive
Statistical rigor
Q.5
The use of low-complexity masking in the BLAST procedure means that it may have higher specificity than FASTA because potential false positives are reduced.
True
False
Q.6
The Dayhoff model of protein evolution is not a Markov process.
True
False
Q.7
In scoring matrices, for convenience, odds scores are converted to log odds scores.
True
False
Q.8
If organisms A, B, and C belong to the same class but to different orders and if organisms D, E, and F belong to the same order but to different families, which of the following pairs of organisms would be expected to show the greatest degree of structural homology?
A and B
A and C
B and D
D and F
Q.9
A phylogenetic tree that is ʺrootedʺ is one
that extends back to the origin of life on Earth
at whose base is located the common ancestor of all taxa depicted on that tree
that illustrates the rampant gene swapping that occurred early in lifeʹs history
that indicates our uncertainty about the evolutionary relationships of the taxa depicted on the tree.
Q.10
For sequences that have ________ a phylogenetic analysis is __________
diverged considerably, more challenging
not diverged, more challenging
diverged considerably, less challenging
diverged considerably, a less work to do
Q.11
Phylogenetic analysis of a set of sequences that aligns ______ is straightforward because the positions that correspond in the sequences can be readily identified in a ______ of the sequences.
very well, multiple sequence alignment
in a haphazard manner, multiple sequence alignment
in a distorted way, multiple sequence alignment
very well, self alignment
Q.12
In the bootstrap method, for branches in the predicted tree topology to be significant, the resampled data sets should frequently predict the same branches.
True
False
Q.13
Tracking the evolutionary history of individual genes in a group of species can reveal which genes have remained in a genome for a long time and which genes have been horizontally transferred between species.
True
False
Q.14
PDB stands for ________________
Protein data bank
Protein Data Base
Protein Derived Base pair
None of these
Q.15
Full form of PIR?
Protein information Report
Protein Information Result
Protein information resource
Protein Information Record
Q.16
Testing humans for a potential genetic disorder is an example of
gene knockout
transgenic studies
genetic screening
gene therapy
Q.17
A technology that combines biological science, computer science, and information technology to enable the discovery of new biological insights and unifying principles
bioethics
bioinformatics
genetic engineering
polymerase chain reaction
Q.18
Used to detect and measure the expression of genes at one time
PCR
gel electrophoresis
DNA fingerprinting
DNA microarray
Q.19
How many TOTAL chromosomes do humans have?
2
44
46
23
Q.20
Which best describes the impact that the Human Genome Project has has on society?
It has helped scientists determine that certain genes can cause diseases
It has led to discrimination against genetically flawed individuals
It has led to the appearance of new diseases
It has cost society billions of dollars without any major benefits
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