Q.1
BLAST often produces several short HSPs rather than a single aligned region.
  • True
  • False
Q.2
BLAST often produces several short HSPs rather than a single aligned region.
  • True
  • False
Q.3
BLAST might not find matches for very short sequences.
  • True
  • False
Q.4
Which of the following is not a benefit of BLAST?
  • Handling of gaps
  • Speed
  • More sensitive
  • Statistical rigor
Q.5
The use of low-complexity masking in the BLAST procedure means that it may have higher specificity than FASTA because potential false positives are reduced.
  • True
  • False
Q.6
The Dayhoff model of protein evolution is not a Markov process.
  • True
  • False
Q.7
In scoring matrices, for convenience, odds scores are converted to log odds scores.
  • True
  • False
Q.8
If organisms A, B, and C belong to the same class but to different orders and if organisms D, E, and F belong to the same order but to different families, which of the following pairs of organisms would be expected to show the greatest degree of structural homology?
  • A and B
  • A and C
  • B and D
  • D and F
Q.9
A phylogenetic tree that is ʺrootedʺ is one
  • that extends back to the origin of life on Earth
  • at whose base is located the common ancestor of all taxa depicted on that tree
  • that illustrates the rampant gene swapping that occurred early in lifeʹs history
  • that indicates our uncertainty about the evolutionary relationships of the taxa depicted on the tree.
Q.10
For sequences that have ________ a phylogenetic analysis is __________
  • diverged considerably, more challenging
  • not diverged, more challenging
  • diverged considerably, less challenging
  • diverged considerably, a less work to do
Q.11
Phylogenetic analysis of a set of sequences that aligns ______ is straightforward because the positions that correspond in the sequences can be readily identified in a ______ of the sequences.
  • very well, multiple sequence alignment
  • in a haphazard manner, multiple sequence alignment
  • in a distorted way, multiple sequence alignment
  • very well, self alignment
Q.12
In the bootstrap method, for branches in the predicted tree topology to be significant, the resampled data sets should frequently predict the same branches.
  • True
  • False
Q.13
Tracking the evolutionary history of individual genes in a group of species can reveal which genes have remained in a genome for a long time and which genes have been horizontally transferred between species.
  • True
  • False
Q.14
PDB stands for ________________
  • Protein data bank
  • Protein Data Base
  • Protein Derived Base pair
  • None of these
Q.15
Full form of PIR?
  • Protein information Report
  • Protein Information Result
  • Protein information resource
  • Protein Information Record
Q.16
Testing humans for a potential genetic disorder is an example of
  • gene knockout
  • transgenic studies
  • genetic screening
  • gene therapy
Q.17
A technology that combines biological science, computer science, and information technology to enable the discovery of new biological insights and unifying principles
  • bioethics
  • bioinformatics
  • genetic engineering
  • polymerase chain reaction
Q.18
Used to detect and measure the expression of genes at one time
  • PCR
  • gel electrophoresis
  • DNA fingerprinting
  • DNA microarray
Q.19
How many TOTAL chromosomes do humans have?
  • 2
  • 44
  • 46
  • 23
Q.20
Which best describes the impact that the Human Genome Project has has on society?
  • It has helped scientists determine that certain genes can cause diseases
  • It has led to discrimination against genetically flawed individuals
  • It has led to the appearance of new diseases
  • It has cost society billions of dollars without any major benefits
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