Q.1
What is reporter genes used for?
  • a) To confirm transformation
  • b) To confirm transfection
  • c) To induce expression
  • d) To cease expression
Q.2
What is “CAT”?
  • a) Repressor gene
  • b) Promoter
  • c) Reporter gene
  • d) Hybrid vector
Q.3
The CAT gene confers antibiotic resistance.
  • a) True
  • b) False
Q.4
Simian Virus(SVis an example of ____________
  • a) Caulimovirus
  • b) Polyomavirus
  • c) Plant virus
  • d) Retrovirus
Q.5
Polyomavirus vectors such as SVare used especially for ____________
  • a) Gene expression
  • b) Gene manipulation
  • c) Recombinant proteins
  • d) Hybrid vector production
Q.6
Which is the first virus to be developed as an animal vector?
  • a) Papillomavirus
  • b) SV40
  • c) Adenovirus
  • d) HIV
Q.7
What is the approximate size of the SVvector?
  • a) 1 kb
  • b) 3 kb
  • c) 5 kb
  • d) 7 kb
Q.8
Transcription in SVis controlled by ___________
  • a) Regulatory element
  • b) Late genes
  • c) Early genes
  • d) Promoter
Q.9
How many proteins are produced during the first stage of SVinfection cycle?
  • a) 1
  • b) 2
  • c) 3
  • d) 4
Q.10
What is the function of the T-antigen of SVviral vectors?
  • a) Genome replication
  • b) Translation
  • c) Transcription
  • d) Conjugation
Q.11
What function does an “oncoprotein” serve?
  • a) Controlled cell proliferation
  • b) Ceased cell proliferation
  • c) Uncontrolled cell proliferation
  • d) Initiates cell proliferation
Q.12
Which type of infection is caused by the human BK virus?
  • a) Viral
  • b) Lytic
  • c) Latent
  • d) Carcinogenic
Q.13
An epstein-barr virus causes a latent infection.
  • a) True
  • b) False
Q.14
What are polyadenylation signals?
  • a) Inducers
  • b) Terminators
  • c) Promoters
  • d) Replicons
Q.15
Which of the following is a source of Poly(A) sites, incorporated into mammalian vectors?
  • a) Mouse beta-globin
  • b) Bovine serum albumin
  • c) Maltose binding protein
  • d) Agrobacterium
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